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rabbit anti-scap  (Thermo Fisher)


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Bioz Manufacturer Symbol Thermo Fisher manufactures this product  
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    Structured Review

    Thermo Fisher rabbit anti-scap
    Rabbit Anti Scap, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+anti-scap/pm38570101-129-80-87
    Average 90 stars, based on 1 article reviews
    rabbit anti-scap - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Cell Culture:

    Article Title: In vivo PAR-CLIP (viP-CLIP) of liver TIAL1 unveils targets regulating cholesterol synthesis and secretion
    Article Snippet: The following antibodies were used in immunoblotting: mouse anti-γ-tubulin (1:10,000) (Sigma-Aldrich, #T6557), rabbit anti-Gapdh (1:500) (Santa Cruz, #2118 S), rabbit anti-HuR (1:500) (Santa Cruz, #sc-20694), rabbit anti-Histone H3 (1:5,000) (Cell Signaling, #4499 S), rabbit anti-apoB (1:2,000) (Meridian, #K23300R), rabbit anti-apoE (1:2,000) (Meridian, #K23100R), rabbit anti-apoA-I (1:10,000) (Meridian, #K23500R), mouse anti-Tial1 (1:1000) (BD Biosciences, #610352), mouse anti-Myc (1:1000) (Millipore, clone 4A6, #05-724), rabbit anti-ßActin (1:5000) (Cell Signaling, #4970 S), rabbit anti-Insig2 (1:250) (ProteinTech, #24766), rabbit anti-Srebp2 (1:500) (ThermoScientific, #PA5-88943), rabbit mouse-Srebp1 (1:500) (ThermoScientific, #MA516124), rabbit anti-Insig1 (1:500) (Abcam, #ab70784), rabbit anti-HMGCR (1:500) (ABclonal, #A19063), rabbit anti-Scap (1:500) (ThermoScientific, #PA5-28982), rabbit anti-HSP90 (1:1000) (Cell Signaling, #4874 S).

    Article Title: Microglial SCAP deficiency protects against diabetes-associated cognitive impairment through inhibiting NLRP3 inflammasome-mediated neuroinflammation.
    Article Snippet: Hyperglycemia-induced pathological microglial responses and subsequent neuronal damage are notable characteristics of diabetes-associated cognitive impairment (DACI).. Cholesterol accumulation in the brain is a prevalent consequence of diabetes mellitus (DM), exacerbating pathological microglial responses.. Regarding disordered glucose and lipid metabolism, the Sterol Regulatory Element-Binding Protein (SREBP) cleavageactivating protein (SCAP), a cholesterol sensor, exhibits increased expression and abnormal translocation from the endoplasmic reticulum to the Golgi, amplifying the inflammatory response.

    Incubation:

    Article Title: In vivo PAR-CLIP (viP-CLIP) of liver TIAL1 unveils targets regulating cholesterol synthesis and secretion
    Article Snippet: The following antibodies were used in immunoblotting: mouse anti-γ-tubulin (1:10,000) (Sigma-Aldrich, #T6557), rabbit anti-Gapdh (1:500) (Santa Cruz, #2118 S), rabbit anti-HuR (1:500) (Santa Cruz, #sc-20694), rabbit anti-Histone H3 (1:5,000) (Cell Signaling, #4499 S), rabbit anti-apoB (1:2,000) (Meridian, #K23300R), rabbit anti-apoE (1:2,000) (Meridian, #K23100R), rabbit anti-apoA-I (1:10,000) (Meridian, #K23500R), mouse anti-Tial1 (1:1000) (BD Biosciences, #610352), mouse anti-Myc (1:1000) (Millipore, clone 4A6, #05-724), rabbit anti-ßActin (1:5000) (Cell Signaling, #4970 S), rabbit anti-Insig2 (1:250) (ProteinTech, #24766), rabbit anti-Srebp2 (1:500) (ThermoScientific, #PA5-88943), rabbit mouse-Srebp1 (1:500) (ThermoScientific, #MA516124), rabbit anti-Insig1 (1:500) (Abcam, #ab70784), rabbit anti-HMGCR (1:500) (ABclonal, #A19063), rabbit anti-Scap (1:500) (ThermoScientific, #PA5-28982), rabbit anti-HSP90 (1:1000) (Cell Signaling, #4874 S).

    Article Title: Microglial SCAP deficiency protects against diabetes-associated cognitive impairment through inhibiting NLRP3 inflammasome-mediated neuroinflammation.
    Article Snippet: Hyperglycemia-induced pathological microglial responses and subsequent neuronal damage are notable characteristics of diabetes-associated cognitive impairment (DACI).. Cholesterol accumulation in the brain is a prevalent consequence of diabetes mellitus (DM), exacerbating pathological microglial responses.. Regarding disordered glucose and lipid metabolism, the Sterol Regulatory Element-Binding Protein (SREBP) cleavageactivating protein (SCAP), a cholesterol sensor, exhibits increased expression and abnormal translocation from the endoplasmic reticulum to the Golgi, amplifying the inflammatory response.



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